Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12560763 | 1.00 | TSHR (0.44) | TSHRTDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL19449972 | 1.00 | TSHR (0.44) | TSHRTDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL12915076 | 1.00 | TSHR (0.44) | TSHRTDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL19450212 | 1.00 | TSHR (0.44) | TSHRTDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL19450283 | 1.00 | TSHR (0.44) | TSHRTDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL1535121 | 0.96 | TSHR (0.47) | TSHRTDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL16675541 | 0.90 | TSHR (0.37) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL10168446 | 0.87 | TSHR (0.50) | TSHRTDP1ALDH1A1 | |
| SCHEMBL827872 | 0.87 | TDP1 (0.50) | TSHRTDP1ALDH1A1LMNA | |
| SCHEMBL15089438 | 0.87 | TDP1 (0.50) | TSHRTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349718-A1 | BINDER SYSTEM | OWENS CORNING INTELLECTUAL CAPITAL, LLC | 2017-12-07 | — | — | US | disclosed |
| US-9651528-B2 | Diarylamine-based fluorogenic probes for detection of peroxynitrite | THE UNIVERSITY OF HONG KONG (CN) | 2017-05-16 | — | — | US | disclosed |
| US-20150217020-A1 | Lung Volume Reduction Therapy Using Crosslinked Non-Natural Polymers | PULMONX CORPORATION | 2015-08-06 | — | — | US | disclosed |
| US-9006340-B2 | Lung volume reduction therapy using crosslinked non-natural polymers | AERIS THERAPEUTICS, LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-8445589-B2 | Lung volume reduction therapy using crosslinked non-natural polymers | AERIS THERAPEUTICS, LLC (US) | 2013-05-21 | — | — | US | disclosed |