Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485335 | 0.93 | MAPT (0.57) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL3492729 | 0.90 | MAPT (0.55) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL3492732 | 0.90 | MAPT (0.55) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL28238029 | 0.84 | MAPT (0.49) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL347800 | 0.82 | RAB9A (0.69) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL247445 | 0.82 | RAB9A (0.69) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL247444 | 0.82 | RAB9A (0.69) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL9559515 | 0.81 | MAPT (0.64) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL28431132 | 0.81 | MAPT (0.68) | MAPTALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL14964811 | 0.81 | MAPT (0.64) | MAPTALDH1A1RAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |