Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627975 | 0.99 | ATM (0.65) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10546962 | 0.97 | ATM (0.67) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| SCHEMBL14970553 | 0.93 | KDM4E (0.66) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| SCHEMBL9195310 | 0.85 | ATM (0.60) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| SCHEMBL9741116 | 0.84 | ATM (0.59) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| SCHEMBL9739717 | 0.82 | ATM (0.62) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9736847 | 0.81 | ATM (0.64) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9736860 | 0.81 | ATM (0.64) | SMN1; SMN2ADRB2ATMMEN1KMT2A | |
| SCHEMBL14970683 | 0.81 | L3MBTL1 (0.71) | SMN1; SMN2MEN1KMT2AKDM4EHTT | |
| SCHEMBL806900 | 0.81 | L3MBTL1 (0.71) | SMN1; SMN2MEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |