Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.88 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.68 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.68 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492315 | 0.95 | MEN1 (0.97) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL5857827 | 0.94 | MEN1 (0.94) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL19287693 | 0.94 | MEN1 (1.00) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL10223295 | 0.91 | PSMB1 (0.82) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL11977007 | 0.89 | MEN1 (0.85) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL9527128 | 0.88 | MEN1 (0.77) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL9528262 | 0.86 | KMT2A (0.75) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL23474922 | 0.86 | MEN1 (0.79) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL491582 | 0.85 | MEN1 (0.69) | MEN1KMT2AHRH3PSMB1PSMB5 | |
| SCHEMBL14287709 | 0.84 | MEN1 (0.76) | MEN1KMT2AHRH3PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |