Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.87 |
| ▸ | RAB9A | P51151 | 3/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.84 |
| ▸ | LTA4H | P09960 | 3/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | NPY1R | P25929 | 1/20 | 0.80 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | HRH1 | P35367 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
| ▸ | HRH2 | P25021 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581020 | 1.00 | NPC1 (0.87) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL4689454 | 0.98 | KDM4E (0.86) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL1387408 | 0.94 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL7400511 | 0.94 | KDM4E (0.85) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL7397895 | 0.94 | KDM4E (0.85) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL7399833 | 0.94 | KDM4E (0.85) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL7402377 | 0.94 | KDM4E (0.85) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| SCHEMBL7400512 | 0.94 | KDM4E (0.85) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| Hydrochloric Acid SCHEMBL7438703 | 0.93 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H | |
| Hydrochloric Acid SCHEMBL7398993 | 0.93 | KDM4E (0.83) | NPC1RAB9ASMN1; SMN2KDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |