Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.66 |
| ▸ | DRD1 | P21728 | 3/20 | 0.66 |
| ▸ | DRD4 | P21917 | 3/20 | 0.66 |
| ▸ | DRD5 | P21918 | 3/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14966375 | 0.99 | HRH1 (0.64) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL14970672 | 0.88 | MEN1 (0.73) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL14970678 | 0.88 | MEN1 (0.73) | HRH1DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL30192529 | 0.87 | MEN1 (0.71) | HRH1DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL14969476 | 0.87 | MEN1 (0.71) | HRH1DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL14966426 | 0.87 | MEN1 (0.71) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL4477130 | 0.86 | L3MBTL1 (0.74) | HRH1DRD1DRD4DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL14966571 | 0.85 | L3MBTL1 (0.72) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11251197 | 0.84 | HRH1 (0.77) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL11599933 | 0.83 | L3MBTL1 (0.68) | HRH1DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |