Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.97 |
| ▸ | BACE1 | P56817 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766268 | 1.00 | KDM4E (0.97) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H | |
| Hydrochloric Acid SCHEMBL14966569 | 0.99 | KDM4E (0.94) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H | |
| SCHEMBL305458 | 0.98 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H | |
| SCHEMBL12323573 | 0.91 | KDM4E (0.86) | KDM4EALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL11941565 | 0.86 | ALDH1A1 (0.77) | KDM4EALDH1A1SMN1; SMN2LTA4HTSHR | |
| SCHEMBL4286569 | 0.85 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H | |
| SCHEMBL6932153 | 0.85 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H | |
| SCHEMBL26986155 | 0.85 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2LTA4HHTT | |
| SCHEMBL15372729 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H | |
| SCHEMBL4283657 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2BACE1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |