Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970454 | 0.99 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL14970722 | 0.81 | SMN1; SMN2 (0.55) | KDM4EMEN1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14966443 | 0.80 | SMN1; SMN2 (0.53) | KDM4EMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8704734 | 0.79 | HRH3 (0.55) | KDM4ELMNASMN1; SMN2TSHRLTA4H | |
| Hydrochloric Acid SCHEMBL8698941 | 0.78 | HRH3 (0.54) | KDM4ELMNASMN1; SMN2TSHRLTA4H | |
| SCHEMBL14970479 | 0.75 | SMN1; SMN2 (0.74) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12120425 | 0.74 | CYP1A2 (0.54) | KDM4EMEN1KMT2ATDP1LMNA | |
| SCHEMBL1307575 | 0.74 | TSHR (0.53) | KDM4ETDP1LMNASMN1; SMN2TSHR | |
| SCHEMBL31641414 | 0.73 | TSHR (0.56) | KDM4ETDP1LMNASMN1; SMN2TSHR | |
| SCHEMBL14970450 | 0.73 | KDM4E (0.92) | KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |