Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14966443 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| SCHEMBL14970726 | 0.89 | TSHR (0.54) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL14966454 | 0.88 | TSHR (0.52) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| SCHEMBL12120425 | 0.87 | CYP1A2 (0.54) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| SCHEMBL8704734 | 0.86 | HRH3 (0.55) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL8698941 | 0.85 | HRH3 (0.54) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| SCHEMBL14970510 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL14970479 | 0.83 | SMN1; SMN2 (0.74) | SMN1; SMN2KDM4ENPC1RAB9ATSHR | |
| SCHEMBL16979837 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4ETSHRLMNAKMT2A | |
| SCHEMBL14970454 | 0.83 | KDM4E (0.59) | SMN1; SMN2KDM4ENPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |