SCHEMBL14970726

SCHEMBL14970726

CCc1ccc(Cl)cc1OCCN1CCCCCC1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
KDM4E B2RXH2 2/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
LMNA P02545 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LTA4H P09960 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2C P28335 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14966454 0.99 TSHR (0.52) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL12120425 0.99 CYP1A2 (0.54) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL14970722 0.89 SMN1; SMN2 (0.55) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL14966443 0.88 SMN1; SMN2 (0.53) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1307575 0.84 TSHR (0.53) TSHRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL14970728 0.82 LTA4H (0.53) TSHRSMN1; SMN2KDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL14966567 0.81 LTA4H (0.52) TSHRSMN1; SMN2KDM4ELTA4H
SCHEMBL14970479 0.80 SMN1; SMN2 (0.74) TSHRCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL14970678 0.80 MEN1 (0.73) TSHRCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL14970672 0.80 MEN1 (0.73) TSHRCYP1A2CYP2D6CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013074965-A1 AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS MICROBIOTIX, INC. (US) 2013-05-23 WO disclosed