Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.38 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497037 | 0.92 | UTS2R (0.38) | UTS2RHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1496897 | 0.91 | UTS2R (0.47) | UTS2RHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1497059 | 0.90 | UTS2R (0.47) | UTS2RHDAC3HDAC1HDAC2NCOR2 | |
| Hydrochloric Acid SCHEMBL1496948 | 0.90 | UTS2R (0.47) | UTS2R | |
| SCHEMBL1496973 | 0.89 | UTS2R (0.47) | UTS2RHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1496910 | 0.87 | UTS2R (0.41) | UTS2R | |
| SCHEMBL1497075 | 0.87 | UTS2R (0.44) | UTS2RHDAC1MAPK1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL1497060 | 0.86 | UTS2R (0.47) | UTS2RHDAC1KMT2A | |
| SCHEMBL1497044 | 0.85 | UTS2R (0.45) | UTS2RKMT2A | |
| SCHEMBL1497187 | 0.85 | UTS2R (0.42) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |