Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497206 | 0.92 | UTS2R (0.46) | UTS2RHDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL1497068 | 0.91 | UTS2R (0.47) | UTS2RALDH1A1HPGD | |
| SCHEMBL1497073 | 0.90 | UTS2R (0.47) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| Hydrochloric Acid SCHEMBL1496948 | 0.89 | UTS2R (0.47) | UTS2R | |
| SCHEMBL1497003 | 0.88 | UTS2R (0.44) | UTS2RRAB9AALDH1A1CYP1A2POLB | |
| SCHEMBL1496971 | 0.86 | UTS2R (0.43) | UTS2RALDH1A1POLBHPGD | |
| SCHEMBL1496910 | 0.86 | UTS2R (0.41) | UTS2R | |
| Hydrochloric Acid SCHEMBL1497060 | 0.85 | UTS2R (0.47) | UTS2RALDH1A1HDAC1 | |
| SCHEMBL1496897 | 0.84 | UTS2R (0.47) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL1497044 | 0.84 | UTS2R (0.45) | UTS2RRAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |