Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575916 | 0.85 | EPHX2 (0.83) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL15224223 | 0.85 | EPHX2 (0.82) | EPHX2TDP1USP2CYP1A2MAPT | |
| SCHEMBL5125065 | 0.84 | EPHX2 (0.71) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL2755805 | 0.79 | EPHX2 (0.68) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL15224222 | 0.79 | EPHX2 (0.72) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL2749570 | 0.79 | HPGD (0.64) | EPHX2CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL4132255 | 0.78 | HPGD (0.62) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL21998666 | 0.78 | HPGD (0.62) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL21998742 | 0.78 | HPGD (0.62) | EPHX2TDP1CYP1A2MAPTCYP2C9 | |
| SCHEMBL15359448 | 0.77 | EPHX2 (0.72) | EPHX2TDP1USP2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892245-B1 | ANTINEOPLASTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | CT INGENIERIA GENETICA BIOTECH (CU) | 2015-07-29 | — | — | EP | claimed |
| EP-1892245-B1 | ANTINEOPLASTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | CT INGENIERIA GENETICA BIOTECH (CU) | 2015-07-29 | — | — | EP | disclosed |
| WO-2013074619-A1 | MATRICES FOR RAPID ALIGNMENT OF GRAPHITIC STRUCTURES FOR STACKED CHIP COOLING APPLICATIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-05-23 | — | — | WO | disclosed |