SCHEMBL1497154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496850	0.95	GAA (0.41)	GAAKDM4EAPOBEC3ACTDSP1APOBEC3G
	SCHEMBL1497163	0.92	GAA (0.36)	GAAPDCD1CD274HDAC1HTR5A
	SCHEMBL1497028	0.89	KDM4E (0.38)	GAAKDM4EAPOBEC3ACTDSP1APOBEC3G
	SCHEMBL1497087	0.88	SLC2A1 (0.41)	GAAKDM4EAPOBEC3ACTDSP1APOBEC3G
	SCHEMBL3229485	0.88	GAA (0.41)	GAAPDCD1CD274MLNRPPARG
	SCHEMBL1496882	0.88	KDM4E (0.42)	GAAKDM4EPDCD1CD274MLNR
	SCHEMBL3227878	0.87	GAA (0.42)	GAAAPOBEC3ACTDSP1APOBEC3GPDCD1
	SCHEMBL1496845	0.87	KDM4E (0.45)	GAAKDM4EALDH1A1USP2LMNA
	SCHEMBL1496831	0.86	KDM4E (0.38)	GAAKDM4EAPOBEC3ACTDSP1APOBEC3G
	SCHEMBL1497145	0.86	KDM4E (0.43)	GAAKDM4ECD274MLNRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.