Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14971867 | 0.92 | DGAT1 (0.60) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14972180 | 0.92 | DGAT1 (0.53) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971673 | 0.92 | DGAT1 (0.59) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971682 | 0.90 | DGAT1 (0.61) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971622 | 0.88 | DGAT1 (0.45) | DGAT1KCNH2SOAT1ADORA2APARP1 | |
| SCHEMBL14971619 | 0.87 | DGAT1 (0.77) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971950 | 0.87 | DGAT1 (0.59) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971902 | 0.86 | DGAT1 (0.61) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971636 | 0.86 | DGAT1 (0.78) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14972157 | 0.85 | DGAT1 (0.75) | DGAT1KCNH2SOAT1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074387-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |