Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.64 |
| ▸ | IDH1 | O75874 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974756 | 0.88 | HSD11B1 (0.69) | HSD11B1IDH1 | |
| SCHEMBL3250173 | 0.83 | HSD11B1 (0.68) | HSD11B1IDH1 | |
| SCHEMBL3250791 | 0.83 | HSD11B1 (0.78) | HSD11B1IDH1 | |
| SCHEMBL3247089 | 0.81 | HSD11B1 (0.77) | HSD11B1IDH1 | |
| SCHEMBL3237276 | 0.78 | HSD11B1 (0.88) | HSD11B1IDH1 | |
| SCHEMBL1973938 | 0.78 | HSD11B1 (1.00) | HSD11B1IDH1 | |
| SCHEMBL3237290 | 0.77 | HSD11B1 (0.75) | HSD11B1IDH1 | |
| SCHEMBL13271536 | 0.76 | HSD11B1 (0.54) | HSD11B1IDH1 | |
| SCHEMBL1971793 | 0.75 | HSD11B1 (0.57) | HSD11B1CNR2CNR1 | |
| SCHEMBL3244325 | 0.75 | HSD11B1 (0.81) | HSD11B1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233480-B1 | Chemical compounds | ASTRAZENECA AB (SE) | 2013-05-29 | — | — | EP | claimed |