Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161766 | 0.90 | MET (0.60) | MET | |
| SCHEMBL1190930 | 0.87 | MET (0.61) | MET | |
| SCHEMBL1161358 | 0.85 | MET (0.59) | MET | |
| SCHEMBL14972797 | 0.83 | MET (0.54) | MET | |
| SCHEMBL1161726 | 0.83 | MET (0.55) | MET | |
| SCHEMBL1161398 | 0.82 | MET (0.57) | MET | |
| SCHEMBL1161263 | 0.81 | MET (0.55) | MET | |
| SCHEMBL14972737 | 0.78 | MET (0.51) | MET | |
| SCHEMBL1160980 | 0.78 | MET (0.53) | MET | |
| SCHEMBL1161552 | 0.74 | MET (0.46) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462143-B1 | 3-HETEROARYLMETHYL-IMIDAZO[1,2-B]PYRIDAZIN-6-YL DERIVATIVES AS C-MET TYROSINE KINASE MODULATORS | NOVARTIS AG (CH) | 2013-05-29 | — | — | EP | claimed |