Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849974 | 0.93 | TSHR (0.57) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL9292497 | 0.93 | TSHR (0.57) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL1982596 | 0.89 | CES1 (0.43) | SLC22A6TSHRALDH1A1TDP1 | |
| SCHEMBL23565474 | 0.87 | ACE (0.46) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL1497330 | 0.84 | EGLN1 (0.52) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL12697091 | 0.84 | CES1 (0.48) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Glutarate SCHEMBL27563696 | 0.84 | SLC22A6 (0.69) | SLC22A6LMNATSHRNFKB1PMP22 | |
| SCHEMBL28080286 | 0.82 | KDM4E (0.40) | SLC22A6LMNATSHRALDH1A1KMT2A | |
| SCHEMBL4819568 | 0.82 | ALDH1A1 (0.45) | LMNAALDH1A1TDP1 | |
| SCHEMBL23565344 | 0.81 | KMT2A (0.50) | SLC22A6LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475375-A2 | PI3 KINASE INHIBITORS AND USES THEREOF | Avila Therapeutics, Inc. (US) | 2012-07-18 | — | — | EP | disclosed |
| CN-102443102-A | Liquid film-forming material and synthesis method thereof | SHAOSHENG DONG | 2012-05-09 | — | — | CN | disclosed |
| US-20110230476-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-09-22 | — | — | US | disclosed |
| WO-2011031896-A2 | PI3 KINASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| EP-1767600-B1 | Ink composition, ink jet recording method, method for producing planographic printing plate and planographic printing plate | FUJIFILM CORP (JP) | 2009-11-18 | — | — | EP | disclosed |
| US-4211566-A | COATING RESIN, PIGMENT, ORGANOTIN COMPOUND TO SHIPS | CHUGOKU MARINE PAINTS LTD. (JP) | 1980-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230476-A1 | PI3 KINASE INHIBITORS AND USES THEREOF | PIK3CA, PIK3CB, PIK3C2B | SLC22A6 4751/4885LMNA 3776/4885TSHR 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.