Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973495 | 0.90 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL12332921 | 0.89 | FYN (0.39) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL2474963 | 0.84 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL2479831 | 0.84 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL14983297 | 0.82 | PDE5A (0.42) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL14629856 | 0.77 | FYN (0.52) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9971217 | 0.74 | CTDSP1 (0.47) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL14973723 | 0.74 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL14983287 | 0.72 | FYN (0.44) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL12332919 | 0.71 | PDE5A (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137869-A1 | LUMINOPHORES | UNIVERSITY OF YORK (UK) | 2013-05-30 | — | — | US | disclosed |
| US-20130137869-A1 | LUMINOPHORES | UNIVERSITY OF YORK (UK) | 2013-05-30 | — | — | US | disclosed |