Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974265 | 1.00 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL16848418 | 0.88 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL14912103 | 0.81 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL14973974 | 0.80 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL14973976 | 0.80 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL14977554 | 0.78 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL14985449 | 0.77 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL14977461 | 0.77 | CNR2 (0.49) | CNR2 | |
| SCHEMBL14974298 | 0.77 | CNR2 (0.49) | CNR2 | |
| SCHEMBL14977377 | 0.74 | CNR2 (0.43) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137676-A1 | NOVEL [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2013-05-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137676-A1 | NOVEL [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | TYMS, TBXA2R, TYMP | CNR2 135/4885CNR1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.