Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974298 | 1.00 | CNR2 (0.49) | CNR2ALDH1A1TP53MAPT | |
| SCHEMBL14911375 | 0.83 | CNR2 (0.54) | CNR2 | |
| SCHEMBL14977498 | 0.81 | CNR2 (0.67) | CNR2 | |
| SCHEMBL14973930 | 0.81 | CNR2 (0.67) | CNR2 | |
| SCHEMBL14974007 | 0.78 | CNR2 (0.53) | CNR2 | |
| SCHEMBL14977326 | 0.78 | CNR2 (0.53) | CNR2 | |
| SCHEMBL14974530 | 0.78 | CNR2 (0.53) | CNR2 | |
| SCHEMBL14974263 | 0.77 | CNR2 (0.48) | CNR2 | |
| SCHEMBL14974265 | 0.77 | CNR2 (0.48) | CNR2 | |
| SCHEMBL14973782 | 0.77 | CNR2 (0.67) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782915-A1 | [1, 2, 3]TRIAZOLO [4, 5 -D]PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-10-01 | — | — | EP | claimed |
| WO-2013076182-A1 | [1, 2, 3]TRIAZOLO [4, 5 -D] PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-30 | — | — | WO | claimed |