Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907358 | 0.83 | CSNK2A1 (0.32) | — | |
| SCHEMBL10410188 | 0.83 | GRIA1 (0.38) | CYP1A2CYP2A6TSHRLMNAGRIA1 | |
| SCHEMBL1745091 | 0.83 | PTGES (0.35) | CYP1A2CYP2A6LMNAMEN1KMT2A | |
| SCHEMBL14975968 | 0.83 | PBRM1 (0.35) | LMNAMEN1KMT2A | |
| SCHEMBL3011522 | 0.81 | NOTUM (0.37) | TSHR | |
| SCHEMBL9729126 | 0.80 | CYP2A6 (0.41) | CYP2A6TSHRLMNAALDH1A1 | |
| SCHEMBL2874737 | 0.77 | CYP1A2 (0.41) | CYP1A2CYP2A6TSHRLMNAALDH1A1 | |
| SCHEMBL2471569 | 0.76 | TSHR (0.57) | CYP1A2CYP2A6TSHRLMNACES1 | |
| SCHEMBL437532 | 0.74 | AHR (0.38) | CYP1A2CYP2A6LMNAALDH1A1MEN1 | |
| SCHEMBL14976960 | 0.74 | CNR2 (0.37) | CES1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782565-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076230-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |