Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MMP14 | P50281 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976505 | 0.76 | NPC1 (0.38) | MEN1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL11564440 | 0.76 | TP53 (0.36) | TDP1ALDH1A1TP53CYP3A4CYP1A2 | |
| SCHEMBL14976960 | 0.74 | CNR2 (0.37) | RORBMEN1KMT2ATDP1DPP4 | |
| SCHEMBL8969966 | 0.74 | CCR1 (0.50) | MAPTTDP1KDM4EALDH1A1LMNA | |
| SCHEMBL2319463 | 0.73 | PDE2A (0.41) | KMT2ANR4A2L3MBTL1 | |
| SCHEMBL15637294 | 0.72 | CNR2 (0.39) | RORBDPP4CNR2S100A4CDC25B | |
| SCHEMBL15067608 | 0.72 | TP53 (0.35) | TDP1ALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL2306238 | 0.72 | DPP4 (0.48) | RORBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL27868401 | 0.71 | CCR1 (0.44) | MEN1MAPTKMT2ATDP1KDM4E | |
| SCHEMBL6682355 | 0.71 | CYP2A6 (0.40) | MEN1MAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782565-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076230-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |