Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050518 | 0.80 | L3MBTL1 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11566539 | 0.80 | FABP3 (0.33) | FABP3FABP4ALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL15067608 | 0.79 | TP53 (0.35) | TP53TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL6682355 | 0.78 | CYP2A6 (0.40) | TP53TSHRALDH1A1CYP2A6CYP1A2 | |
| SCHEMBL14976333 | 0.76 | RORB (0.38) | TP53CYP3A4TDP1MAPK1ALDH1A1 | |
| SCHEMBL17999104 | 0.76 | ACHE (0.37) | CYP3A4FABP3FABP4ALDH1A1 | |
| SCHEMBL3022644 | 0.75 | ALOX5 (0.42) | TP53TSHR | |
| SCHEMBL4438343 | 0.75 | TP53 (0.41) | TP53TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL435005 | 0.75 | AHR (0.45) | TP53TSHRCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL436851 | 0.74 | AHR (0.38) | TP53TSHRCYP3A4TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782565-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076230-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| US-4150158-A | Oxadiazindione derivatives useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |