Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26538480 | 0.81 | KDM4E (0.63) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL14976996 | 0.77 | CHEK1 (0.51) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL20223634 | 0.77 | KDM4E (0.50) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| Hydrochloric Acid SCHEMBL1203301 | 0.72 | DYRK1A (0.46) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL7332574 | 0.71 | CHEK1 (0.49) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL15358474 | 0.70 | TSHR (0.39) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL16678534 | 0.69 | PKM (0.48) | PKMCLK1 | |
| SCHEMBL9913664 | 0.69 | EPHB3 (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL13995840 | 0.67 | KDM4E (1.00) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL31641304 | 0.66 | CLK1 (0.43) | KDM4EALDH1A1RECQLSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |