Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 6/20 | 0.34 |
| ▸ | HTR1D | P28221 | 6/20 | 0.34 |
| ▸ | HTR1B | P28222 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553263 | 0.84 | KCNH2 (0.43) | KCNH2PDPK1MAPTTDP1 | |
| SCHEMBL7601917 | 0.79 | KCNH2 (0.39) | KCNH2PDPK1 | |
| SCHEMBL11501196 | 0.79 | KCNH2 (0.42) | KCNH2PDPK1 | |
| SCHEMBL1691751 | 0.79 | LMNA (0.35) | LMNAPDPK1CDK1CDK2CCNB1 | |
| SCHEMBL4274960 | 0.77 | CDK1 (0.37) | LMNAPDPK1CDK1CDK2CCNB1 | |
| SCHEMBL22322083 | 0.75 | CDK1 (0.43) | LMNAPDPK1CDK1CDK2CCNB1 | |
| SCHEMBL7701413 | 0.74 | KCNH2 (0.47) | KCNH2PDPK1 | |
| SCHEMBL1063754 | 0.74 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL278227 | 0.74 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL730079 | 0.73 | KCNH2 (0.50) | KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013077989-A1 | PROCESS FOR PREPARATION OF ALUMINUM SALT OF PHOSPHONIC ACID ESTER | ICL-IP AMERICA INC. (US) | 2013-05-30 | — | — | WO | disclosed |