Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 3/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977197 | 0.90 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977774 | 0.89 | KMT2A (0.58) | MEN1KMT2ANPC1RAB9ATAS1R3 | |
| SCHEMBL14977161 | 0.89 | RAB9A (0.64) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977611 | 0.89 | DHODH (0.64) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977531 | 0.88 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977401 | 0.88 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977360 | 0.87 | NPC1 (0.56) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977542 | 0.87 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977807 | 0.87 | KMT2A (0.67) | MEN1KMT2ANPC1RAB9ADHODH | |
| SCHEMBL14977144 | 0.86 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |