Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.67 |
| ▸ | GALR3 | O60755 | 1/20 | 0.67 |
| ▸ | TNF | P01375 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985304 | 0.96 | DHODH (0.81) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14985273 | 0.88 | RAB9A (0.74) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL20983027 | 0.84 | KMT2A (1.00) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14977355 | 0.84 | KMT2A (1.00) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14977356 | 0.84 | KMT2A (1.00) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14985289 | 0.84 | RAB9A (0.71) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14977605 | 0.84 | RAB9A (0.68) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14985277 | 0.82 | POLB (0.71) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14985364 | 0.82 | KMT2A (0.73) | DHODHRAB9ANR2F2KMT2AGAA | |
| SCHEMBL14977813 | 0.80 | KMT2A (0.70) | DHODHRAB9ANR2F2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |