Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 12/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523099 | 1.00 | GHSR (0.61) | GHSRAGTR1XIAP | |
| Trifluoroacetic Acid SCHEMBL8716938 | 0.96 | GHSR (0.57) | GHSRAGTR1XIAP | |
| SCHEMBL8717060 | 0.93 | GHSR (0.54) | GHSRAGTR1XIAP | |
| SCHEMBL9025202 | 0.88 | GHSR (0.62) | GHSRAGTR1XIAP | |
| SCHEMBL9024318 | 0.88 | GHSR (0.62) | GHSRAGTR1XIAP | |
| L-158432 SCHEMBL7417293 | 0.87 | GHSR (0.76) | GHSRAGTR1XIAP | |
| L-158432 SCHEMBL9023762 | 0.87 | GHSR (0.76) | GHSRAGTR1XIAP | |
| SCHEMBL9024548 | 0.86 | GHSR (0.66) | GHSRAGTR1XIAP | |
| SCHEMBL9024158 | 0.86 | GHSR (0.66) | GHSRAGTR1XIAP | |
| SCHEMBL8909523 | 0.86 | GHSR (0.64) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450268-B2 | Methods of using macrocyclic modulators of the ghrelin receptor | TRANZYME PHARMA INC. (CA) | 2013-05-28 | — | — | US | disclosed |
| US-8450268-B2 | Methods of using macrocyclic modulators of the ghrelin receptor | TRANZYME PHARMA INC. (CA) | 2013-05-28 | — | — | US | disclosed |