Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174217 | 0.95 | KCNH2 (0.50) | KCNH2NQO1CNR2KMT2ALTB4R | |
| SCHEMBL26319795 | 0.95 | KCNH2 (0.50) | KCNH2NQO1CNR2KMT2ALTB4R | |
| SCHEMBL19607554 | 0.92 | NQO1 (0.54) | NQO1CNR2KMT2AMAPTCACNA2D1 | |
| SCHEMBL12680650 | 0.92 | NQO1 (0.54) | NQO1CNR2KMT2AMAPTCACNA2D1 | |
| SCHEMBL25548722 | 0.86 | NQO1 (0.61) | KCNH2NQO1CNR2LTB4RLTB4R2 | |
| SCHEMBL19017946 | 0.84 | NQO1 (0.64) | NQO1KMT2ARAB9ATP53 | |
| SCHEMBL14354848 | 0.83 | MAPT (0.46) | KMT2AMAPTRAB9AFFAR1LMNA | |
| SCHEMBL15496801 | 0.83 | RELA (0.56) | NQO1KMT2AMAPTRAB9ATP53 | |
| SCHEMBL15499120 | 0.83 | RELA (0.56) | NQO1KMT2AMAPTRAB9ATP53 | |
| SCHEMBL2492122 | 0.82 | NQO1 (0.67) | NQO1MAPTRAB9ACACNA2D1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450033-B2 | Electrography; facsimiles, printers, copiers; polyurethanes | RICOH COMPANY, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |