SCHEMBL14979543

SCHEMBL14979543

C[Si](C)(C1=CC=CCC1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874254 0.85 ESR1 (0.31) ESR1ESR2
SCHEMBL7055264 0.82 ESR1 (0.42) ESR1ESR2NR1H2NR1H3
SCHEMBL24443013 0.81
SCHEMBL22200168 0.80
SCHEMBL15927198 0.78
SCHEMBL21181868 0.78
SCHEMBL18323819 0.78
SCHEMBL25767039 0.76
SCHEMBL22110038 0.74
SCHEMBL19755895 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013073874-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND AN ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-05-23 WO disclosed