SCHEMBL7055264

SCHEMBL7055264

C[Si](C)(C1=CC=CC1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4652615 0.83 ESR1 (0.33) ESR1ESR2NR1H2NR1H3
SCHEMBL7049972 0.83 ESR1 (0.33) ESR1ESR2NR1H2NR1H3
SCHEMBL14979543 0.82 ESR1 (0.38) ESR1ESR2NR1H2NR1H3
SCHEMBL9145200 0.82 ESR1 (0.32) ESR1ESR2NR1H2NR1H3
SCHEMBL9143179 0.82 ESR1 (0.32) ESR1ESR2NR1H2NR1H3
SCHEMBL7055426 0.81 ESR1 (0.30) ESR1ESR2
SCHEMBL4651356 0.81 ESR1 (0.30) ESR1ESR2
SCHEMBL7056345 0.81 ESR1 (0.30) ESR1ESR2
SCHEMBL8971866 0.80 ESR1 (0.31) ESR1ESR2
SCHEMBL61232 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689359-B Laminate, method for producing same, and method for producing electronic component 道康宁东丽株式会社 2022-04-05 CN disclosed
CN-110256622-B Reinforced and toughened syndiotactic polystyrene and preparation method thereof 中国科学院长春应用化学研究所 2021-03-16 CN disclosed
CN-102666561-B Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN disclosed
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed