SCHEMBL1497963

SCHEMBL1497963

O=C1C=Nc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.42
MAOA P21397 2/20 0.42
IDO1 P14902 1/20 0.42
MAOB P27338 1/20 0.42
AKT1 P31749 1/20 0.42
SNCA P37840 1/20 0.42
MAP2K1 Q02750 1/20 0.42
PIN1 Q13526 1/20 0.42
EHMT2 Q96KQ7 1/20 0.42
NSD1 Q96L73 1/20 0.42
EHMT1 Q9H9B1 1/20 0.42
KMT2A Q03164 7/20 0.41
MEN1 O00255 6/20 0.41
MAPT P10636 5/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 1/20 0.41
EIF2AK2 P19525 1/20 0.41
ALDH1A1 P00352 3/20 0.39
GLRA3 O75311 2/20 0.39
POLB P06746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29409962 1.00 CDC25B (0.42) CDC25BMAOAIDO1MAOBAKT1
Methane SCHEMBL28363844 0.98 KMT2A (0.40) CDC25BMAOAIDO1MAOBAKT1
Hydrochloric Acid SCHEMBL10863150 0.98 KMT2A (0.40) CDC25BMAOAIDO1MAOBAKT1
Hydrochloric Acid SCHEMBL10860848 0.98 KMT2A (0.40) CDC25BMAOAIDO1MAOBAKT1
Potassium SCHEMBL31207020 0.98 KMT2A (0.40) CDC25BMAOAIDO1MAOBAKT1
Phosphoric Acid SCHEMBL29216371 0.89 MAPT (0.40) CDC25BMAOAIDO1MAOBAKT1
SCHEMBL3839654 0.86 MEN1 (0.42) CDC25BMAOAIDO1MAOBAKT1
Hydrochloric Acid SCHEMBL5733204 0.84 MEN1 (0.40) CDC25BMAOAIDO1MAOBAKT1
Indole SCHEMBL21408188 0.79 CA1 (0.53) MAOAMAOBKMT2AMEN1MAPT
SCHEMBL7602072 0.78 KMT2A (0.35) KMT2AMEN1MAPTL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) 2025-09-25 US claimed
WO-2025021115-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2025-01-30 WO claimed
US-20240349762-A1 PIGMENT FOR MEAT SUBSTITUTE COMPOSITIONS CARGILL, INCORPORATED (US) 2024-10-24 US claimed
EP-4326890-A1 PIGMENT FOR MEAT SUBSTITUTE COMPOSITIONS Cargill, Incorporated (US) 2024-02-28 EP claimed
CN-117603121-A C (sp) of indol-3-one 3 ) Process for preparing-H aminated derivatives 温州医科大学 2024-02-27 CN claimed
CN-117412975-A Heterocyclic compounds and their use 伊科诺姆有限公司 2024-01-16 CN claimed
CN-117203345-A Pigments for meat substitute compositions 嘉吉公司 2023-12-08 CN claimed
CN-116751150-A Synthesis method of 2-indolyl substituted indol-3-one compound 福建医科大学 2023-09-15 CN claimed
CN-111545247-B SBA-15 supported multiphase chiral phosphine gold catalyst and preparation method and application thereof 华东师范大学 2023-06-09 CN claimed
WO-2022225781-A1 PIGMENT FOR MEAT SUBSTITUTE COMPOSITIONS CARGILL, INCORPORATED (US) 2022-10-27 WO claimed
US-20170073499-A1 LATEX COMPRISING COLORANT AND METHODS OF MAKING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2017-03-16 US claimed
US-9580578-B2 Latex comprising colorant and methods of making the same XEROX CORPORATION (US) 2017-02-28 US claimed
US-8551188-B2 Composition comprising a hydrophobic dye, a particular organic and/or mineral alkaline agent, a particular compound (I) and a particular organic compound (II), and dyeing use thereof L'OREAL (FR) 2013-10-08 US claimed
US-20120204357-A1 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF L'OREAL (FR) 2012-08-16 US claimed
EP-2473152-A2 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING L'Oréal (FR) 2012-07-11 EP claimed
WO-2011027077-A2 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING L'OREAL (FR) 2011-03-10 WO claimed
WO-2011027076-A2 DYEING METHOD CONSISTING IN APPLYING A METALLIC SALT AND A COMPOSITION CONTAINING A HYDROPHOBIC DYE AND A SPECIFIC COMPOUND L'OREAL (FR) 2011-03-10 WO claimed
WO-2008125658-A1 4,5,11,11A-TETRAHYDRO-1H,6H-OXAZOLO[3',4':1,6]PYRIDO[3,4-B]INDOL-3-ONE DERIVATIVES AND THERAPEUTIC USE THEREOF FOURTILLAN (FR) 2008-10-23 WO claimed
EP-0711299-A1 AZABICYCLOALKYL DERIVATIVES OF IMIDAZO(1,5-a)INDOL-3-ONE AS 5HT 3 ANTAGONISTS PHARMACIA & UPJOHN S.p.A. (IT) 1996-05-15 EP claimed
WO-1995032209-A1 AZABICYCLOALKYL DERIVATIVES OF IMIDAZO(1,5-a)INDOL-3-ONE AS 5HT3 ANTAGONISTS PHARMACIA S.P.A. (IT) 1995-11-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120204357-A1 COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF KRT18, DSG1, DSC1 CDC25B 3180/4885MAOA 3339/4885IDO1 3626/4885
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SCN8A, SCN11A, TRPV1 CDC25B 4519/4885MAOA 3496/4885IDO1 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.