Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5900978 | 0.79 | LOXL2 (0.43) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL15157661 | 0.79 | SLC6A4 (0.52) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL8514968 | 0.79 | LOXL2 (0.43) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28699275 | 0.79 | LOXL2 (0.48) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL14448531 | 0.79 | LOXL2 (0.43) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7649730 | 0.78 | LOXL2 (0.42) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL29003420 | 0.77 | CYP19A1 (0.41) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL391676 | 0.76 | LOXL2 (0.41) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL27858315 | 0.76 | SCN10A (0.44) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 | |
| SCHEMBL391675 | 0.76 | LOXL2 (0.41) | LOXL2CYP19A1CYP2A6CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2634191-A1 | Process for preparing derivatives of thienopyrimidinedione | Glenmark Pharmaceuticals S.A. (CH) | 2013-09-04 | — | — | EP | disclosed |
| EP-2411396-B1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |