Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977583 | 0.91 | RAB9A (0.68) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977713 | 0.90 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977161 | 0.90 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977611 | 0.90 | DHODH (0.64) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977486 | 0.89 | RAB9A (0.62) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977533 | 0.89 | KMT2A (0.78) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977709 | 0.88 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977144 | 0.86 | MEN1 (0.61) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977531 | 0.86 | MEN1 (0.61) | NPC1RAB9AMEN1KMT2ANOD1 | |
| SCHEMBL14977807 | 0.84 | KMT2A (0.67) | NPC1RAB9AMEN1KMT2ANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |