Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640644 | 0.87 | GLS (1.00) | GLS | |
| SCHEMBL21443372 | 0.83 | GLS (0.83) | GLS | |
| SCHEMBL14977106 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL12186903 | 0.82 | GLS (0.67) | GLS | |
| SCHEMBL21443368 | 0.82 | GLS (0.88) | GLS | |
| SCHEMBL14987614 | 0.82 | GLS (1.00) | GLS | |
| SCHEMBL14987561 | 0.82 | GLS (1.00) | GLS | |
| SCHEMBL20340835 | 0.81 | GLS (0.86) | GLS | |
| SCHEMBL14987420 | 0.79 | GLS (0.79) | GLS | |
| SCHEMBL14987469 | 0.79 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078123-A1 | HETEROCYCLIC INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES INC. (US) | 2013-05-30 | — | — | WO | disclosed |