Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765920 | 0.91 | S1PR1 (0.33) | S1PR1S1PR3VDRESR2 | |
| SCHEMBL1498752 | 0.82 | S1PR1 (0.36) | S1PR1S1PR3VDR | |
| SCHEMBL3434745 | 0.64 | AOC3 (0.35) | — | |
| SCHEMBL3396671 | 0.63 | AOC3 (0.34) | S1PR1S1PR3VDR | |
| SCHEMBL14897940 | 0.60 | S1PR1 (0.32) | S1PR1S1PR3 | |
| SCHEMBL3426387 | 0.60 | — | — | |
| SCHEMBL3692899 | 0.59 | KDM4E (0.43) | — | |
| SCHEMBL28815699 | 0.57 | KDM4E (0.40) | — | |
| SCHEMBL1499217 | 0.56 | — | — | |
| SCHEMBL28726107 | 0.54 | CYP3A4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |