Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765920 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3VDR | |
| SCHEMBL1498769 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3VDR | |
| SCHEMBL3396671 | 0.75 | AOC3 (0.34) | S1PR1S1PR3AOC3ABCB11ADORA3 | |
| SCHEMBL3434745 | 0.73 | AOC3 (0.35) | AOC3ABCB11ADORA3ARCYP2D6 | |
| SCHEMBL30301261 | 0.64 | ALOX15 (0.36) | ARVDR | |
| SCHEMBL169822 | 0.64 | ALOX15 (0.36) | ARVDR | |
| SCHEMBL14897940 | 0.64 | S1PR1 (0.32) | S1PR1S1PR3AOC3CYP2D6 | |
| SCHEMBL560872 | 0.63 | ALDH1A1 (0.34) | VDR | |
| SCHEMBL29779644 | 0.63 | ALDH1A1 (0.34) | VDR | |
| SCHEMBL3692899 | 0.62 | KDM4E (0.43) | AOC3CYP2D6LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |