Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 7/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899572 | 0.92 | GRM5 (0.33) | MDM2NR3C2P2RX7 | |
| SCHEMBL900097 | 0.90 | MDM2 (0.30) | MDM2NR3C2 | |
| SCHEMBL899939 | 0.87 | TRPC5 (0.34) | MDM2NR3C2 | |
| SCHEMBL899125 | 0.87 | NR3C2 (0.33) | MDM2NR3C2AOC3P2RX7 | |
| SCHEMBL899670 | 0.84 | NR3C2 (0.36) | MDM2NR3C2 | |
| SCHEMBL898785 | 0.84 | NR3C2 (0.33) | MDM2NR3C2 | |
| SCHEMBL899633 | 0.82 | NR3C2 (0.35) | MDM2NR3C2 | |
| SCHEMBL898787 | 0.80 | TRPC5 (0.33) | MDM2NR3C2 | |
| SCHEMBL898060 | 0.80 | TRPC5 (0.33) | MDM2NR3C2 | |
| SCHEMBL899221 | 0.80 | GLA (0.36) | NR3C2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | claimed |
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | CYP1A1, CYP1B1, CYP2E1 | MDM2 1415/4885NR3C2 2193/4885F2RL1 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.