SCHEMBL149908

SCHEMBL149908

CCCCC/C(=N\OC(=O)c1ccccc1)C(=O)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.47
CES1 P23141 4/20 0.47
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39
PKM P14618 4/20 0.39
CDK5 Q00535 3/20 0.39
CDK5R1 Q15078 3/20 0.39
MAPT P10636 2/20 0.39
KLF5 Q13887 2/20 0.38
TNF P01375 1/20 0.38
NOD1 Q9Y239 1/20 0.38
PAX8 Q06710 2/20 0.38
NR2F2 P24468 1/20 0.38
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149909 1.00 CES2 (0.47) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL13009339 1.00 CES2 (0.47) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL103376 0.99 CES2 (0.48) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL22729193 0.99 CES2 (0.48) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL12021972 0.99 CES2 (0.48) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL92006 0.99 CES2 (0.48) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL123398 0.99 CES2 (0.48) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL21409907 0.96 CES2 (0.46) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL13415039 0.96 CES2 (0.46) CES2CES1ALDH1A1HPGDSMN1; SMN2
SCHEMBL17445967 0.96 CES2 (0.46) CES2CES1ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
US-20230213858-A1 MANUFACTURING METHOD FOR CURED SUBSTANCE, MANUFACTURING METHOD FOR LAMINATE, AND MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-11492552-B2 Polymerizable liquid crystal material, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, polarizing plate, anti-reflection film, display device, and method of producing polymerizable liquid crystal composition ZEON CORPORATION (JP) 2022-11-08 US disclosed
WO-2022196987-A1 ADHESIVE COMPOSITION, AND ADHESIVE SHEET, OPTICAL MEMBER, AND DISPLAY APPARATUS PRODUCED USING SAME 동우 화인켐 주식회사 2022-09-22 WO disclosed
WO-2022186641-A1 ADHESIVE COMPOSITION, ADHESIVE SHEET PREPARED BY USING SAME, OPTICAL MEMBER, AND DISPLAY DEVICE 동우 화인켐 주식회사 2022-09-09 WO disclosed
US-8133656-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-03-13 US disclosed
US-8133656-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-03-13 US disclosed
US-20120057098-A1 COLOR LIQUID CRYSTAL DISPLAY DEVICE CHI MEI CORPORATION (TW) 2012-03-08 US disclosed
US-20110228201-A1 Photosensitive resin composition for color filter and color filter using same CHI-MEI CORPORATION 2011-09-22 US disclosed
US-20110215284-A1 Color composition for color filter, color filter using the composition and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2011-09-08 US disclosed
US-20100295002-A1 Color composition for color filter, color filter using the composition and liquid crystal display device TOPPAN PRINTING CO., LTD. (JP) 2010-11-25 US disclosed
US-20100075254-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-03-25 US disclosed
US-20100075254-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-03-25 US disclosed
EP-2128132-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR COMPRISING THE COMPOUND Adeka Corporation (JP) 2009-12-02 EP disclosed
US-20090004578-A1 RADIATION-SENSITIVE COMPOSITION FOR FORMING COLOR FILTER FOR SOLID-STATE IMAGE SENSING DEVICE, COLOR FILTER, AND SOLID-STATE IMAGE SENSING DEVICE JSR CORPORATION (JP) 2009-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075254-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME CYP4A11, OXER1, NR2E3 CES2 333/4885CES1 474/4885ALDH1A1 2514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.