Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992318 | 0.99 | THRA (0.45) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14975106 | 0.99 | THRA (0.45) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14974433 | 0.96 | TSHR (0.41) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14974791 | 0.95 | KDM4E (0.39) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14992009 | 0.91 | THRA (0.45) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14992221 | 0.91 | THRA (0.45) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14974954 | 0.91 | THRA (0.45) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14974592 | 0.91 | MAPK1 (0.39) | THRATHRBTSHRTP53CYP3A4 | |
| SCHEMBL14974925 | 0.89 | THRA (0.42) | THRATHRBTSHRTP53MAPK1 | |
| SCHEMBL14974863 | 0.89 | THRA (0.37) | THRATHRBTSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785752-A1 | INTERNAL ELECTRON DONOR FOR OLEFIN POLYMERIZATION CATALYSTS, METHOD OF MAKING AND USING THE SAME | BASF Corporation (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082631-A1 | INTERNAL ELECTRON DONOR FOR OLEFIN POLYMERIZATION CATALYSTS, METHOD OF MAKING AND USING THE SAME | BASF CORPORATION (US) | 2013-06-06 | — | — | WO | disclosed |