Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410995 | 0.83 | ERN1 (0.32) | ALDH1A1 | |
| SCHEMBL22833975 | 0.83 | ERN1 (0.32) | ALDH1A1 | |
| SCHEMBL2463070 | 0.79 | CES1 (0.32) | — | |
| SCHEMBL14992458 | 0.79 | CYP3A4 (0.38) | ALDH1A1CYP3A4 | |
| SCHEMBL21495062 | 0.78 | POLB (0.39) | ALDH1A1TSHR | |
| SCHEMBL2467572 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2461408 | 0.76 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL14993162 | 0.76 | MAPT (0.33) | TSHR | |
| SCHEMBL2462924 | 0.76 | NPSR1 (0.39) | ALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL2464227 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785714-A1 | IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | Taivex Therapeutics Corporation (TW) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082324-A1 | IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | TAIVEX THERAPEUTICS CORPORATION (TW) | 2013-06-06 | — | — | WO | disclosed |