Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 1.00 |
| ▸ | FADS1 | O60427 | 4/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CBR1 | P16152 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678733 | 0.83 | GRM5 (0.70) | GRM5NPC1RAB9AKEAP1KMT2A | |
| SCHEMBL678702 | 0.80 | GRM5 (0.66) | GRM5NPC1RAB9AKMT2ATP53 | |
| SCHEMBL25669217 | 0.78 | GRM5 (0.64) | GRM5FADS1P2RX1P2RX4P2RX7 | |
| SCHEMBL16339265 | 0.78 | GRM5 (0.64) | GRM5MAOBNPC1RAB9AKEAP1 | |
| SCHEMBL1874966 | 0.78 | GRM5 (0.61) | GRM5FADS1NPC1RAB9AKMT2A | |
| SCHEMBL15778699 | 0.77 | FADS1 (0.68) | GRM5FADS1P2RX1P2RX4P2RX7 | |
| SCHEMBL20551983 | 0.77 | GRM5 (0.62) | GRM5NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL20552363 | 0.77 | GRM5 (0.62) | GRM5NPC1RAB9AKMT2ATP53 | |
| SCHEMBL3924976 | 0.77 | GRM5 (0.62) | GRM5FADS1P2RX1P2RX4P2RX7 | |
| SCHEMBL2129113 | 0.76 | FADS1 (0.71) | GRM5FADS1P2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011507537-A | — | — | 2011-03-10 | — | — | JP | claimed |