Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195290 | 1.00 | EPHX1 (0.55) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5197203 | 0.86 | EPHX1 (0.51) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5196890 | 0.83 | EPHX1 (0.49) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5196050 | 0.82 | EPHX1 (0.47) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5196840 | 0.80 | CTSK (0.47) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5194663 | 0.80 | CTSK (0.47) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5197134 | 0.80 | CTSK (0.47) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5196344 | 0.80 | CTSK (0.47) | EPHX1MEN1KMT2AHPGDTP53 | |
| SCHEMBL5197253 | 0.80 | NPC1 (0.47) | KMT2ACES1CES2MAPTALDH1A1 | |
| SCHEMBL10942440 | 0.78 | EPHX1 (0.69) | EPHX1MEN1KMT2AHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011508053-A | — | — | 2011-03-10 | — | — | JP | claimed |
| EP-2242776-A1 | MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS | BASF Corporation (US) | 2010-10-27 | — | — | EP | claimed |
| WO-2009088596-A1 | MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS | BASF CATALYSTS LLC (US) | 2009-07-16 | — | — | WO | claimed |
| CN-104903359-B | Method for forming polymerization catalysts with controlled catalyst properties and use thereof in olefin polymerization | 格雷斯公司 | 2018-05-08 | — | — | CN | disclosed |