Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991478 | 0.93 | ACHE (0.38) | ACHEESR1ESR2CYP1A2CYP3A4 | |
| SCHEMBL28085916 | 0.82 | ESR2 (0.46) | ACHEESR1ESR2PLA2G2APLA2G4A | |
| SCHEMBL21435747 | 0.82 | ESR2 (0.46) | ACHEESR1ESR2PLA2G2APLA2G4A | |
| SCHEMBL19283276 | 0.82 | ESR2 (0.46) | ACHEESR1ESR2PLA2G2APLA2G4A | |
| SCHEMBL5599347 | 0.82 | ESR2 (0.46) | ACHEESR1ESR2PLA2G2APLA2G4A | |
| SCHEMBL2964995 | 0.82 | ESR2 (0.46) | ACHEESR1ESR2PLA2G2APLA2G4A | |
| SCHEMBL28284621 | 0.81 | CA12 (0.38) | CYP1A2CYP2C19DHFR | |
| SCHEMBL27900569 | 0.81 | ACHE (0.44) | ACHEESR1ESR2 | |
| SCHEMBL29662092 | 0.80 | ACHE (0.45) | ACHEESR1ESR2PLA2G2APLA2G4A | |
| SCHEMBL994958 | 0.80 | ACHE (0.45) | ACHEESR1ESR2PLA2G2APLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786433-A1 | ORGANIC ELECTRONIC DEVICE | Novaled GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013079676-A1 | ORGANIC ELECTRONIC DEVICE | NOVALED AG (DE) | 2013-06-06 | — | — | WO | disclosed |