Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161161 | 0.89 | MEN1 (0.46) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL18044234 | 0.89 | MEN1 (0.59) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL15120152 | 0.89 | MEN1 (0.59) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL14988691 | 0.88 | MEN1 (0.58) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL14988693 | 0.88 | MEN1 (0.58) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL15161141 | 0.86 | MEN1 (0.47) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL14997208 | 0.85 | SENP2 (0.50) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL15161158 | 0.85 | MEN1 (0.44) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL15161162 | 0.85 | MEN1 (0.44) | MEN1ALDH1A1APPMAPTTHRB | |
| SCHEMBL17056189 | 0.84 | SUMO2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599771-A1 | NAPHTHALENE DERIVATIVE | Daito Chemix Corporation (JP) | 2013-06-05 | — | — | EP | disclosed |