Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619086 | 0.87 | ALDH1A1 (0.41) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL18533427 | 0.82 | NPC1 (0.47) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL13665501 | 0.81 | DPP4 (0.49) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL1712955 | 0.81 | DPP4 (0.49) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL1712954 | 0.81 | DPP4 (0.45) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL16083084 | 0.79 | ALDH1A1 (0.57) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL14311809 | 0.79 | DPP7 (0.51) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL10272430 | 0.79 | DPP4 (0.51) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL13974450 | 0.79 | DPP7 (0.51) | DPP4DPP7CHRM2CHRM4CHRM1 | |
| SCHEMBL8246597 | 0.79 | DPP7 (0.51) | DPP4DPP7CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847532-B1 | IGF-1R INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |