Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267541 | 0.91 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29494818 | 0.91 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL258759 | 0.91 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL30388311 | 0.85 | NPC1 (0.42) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL23050234 | 0.85 | NPC1 (0.59) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL14323153 | 0.85 | NPC1 (0.59) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL14323914 | 0.85 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL11373760 | 0.83 | NPC1 (0.57) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL14199113 | 0.82 | NPC1 (0.50) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL30545220 | 0.82 | NPC1 (0.39) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8728712-B2 | Polymerizable composition | FUJIFILM CORPORATION (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20130143164-A1 | POLYMERIZABLE COMPOSITION | FUJIFILM CORPORATION (JP) | 2013-06-06 | — | — | US | disclosed |