Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085973 | 0.96 | LARS1 (0.53) | LARS1LMNAF2KDM4EALDH1A1 | |
| SCHEMBL15000281 | 0.92 | F2 (0.49) | LARS1F2PLG | |
| SCHEMBL15000276 | 0.92 | LARS1 (0.53) | LARS1LMNAF2KDM4EALDH1A1 | |
| SCHEMBL14999926 | 0.91 | SLC16A3 (0.49) | LARS1F2SLC16A3ALDH1A1PLG | |
| SCHEMBL13152388 | 0.91 | LARS1 (0.50) | LARS1LMNAF2ALDH1A1NPY5R | |
| SCHEMBL18383338 | 0.91 | LARS1 (0.50) | LARS1LMNAF2ALDH1A1NPY5R | |
| SCHEMBL18387777 | 0.91 | LARS1 (0.50) | LARS1F2KMT2APOLB | |
| SCHEMBL14999902 | 0.90 | LARS1 (0.52) | LARS1F2KDM4EALDH1A1KMT2A | |
| SCHEMBL15000247 | 0.90 | LARS1 (0.49) | LARS1F2CNR2POLB | |
| SCHEMBL3091892 | 0.90 | LARS1 (0.49) | LARS1LMNAF2ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |