Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 12/20 | 0.62 |
| ▸ | GLP1R | P43220 | 8/20 | 0.56 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256863 | 0.96 | FOLH1 (0.60) | FOLH1GLP1R | |
| SCHEMBL16256862 | 0.92 | FOLH1 (0.54) | FOLH1GLP1R | |
| SCHEMBL19182223 | 0.92 | FOLH1 (0.65) | FOLH1GLP1RRIMKLANAALAD2 | |
| SCHEMBL19248260 | 0.89 | GLP1R (0.64) | FOLH1GLP1RRIMKLANAALAD2 | |
| SCHEMBL11986385 | 0.88 | FOLH1 (0.61) | FOLH1GLP1RRIMKLANAALAD2 | |
| SCHEMBL17508865 | 0.88 | FOLH1 (0.61) | FOLH1GLP1RRIMKLANAALAD2 | |
| SCHEMBL10134673 | 0.88 | FOLH1 (0.58) | FOLH1GLP1R | |
| SCHEMBL23425336 | 0.87 | GLP1R (0.66) | FOLH1GLP1R | |
| SCHEMBL21344719 | 0.86 | FOLH1 (0.72) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL27143006 | 0.85 | GLP1R (0.57) | FOLH1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10653806-B2 | Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-05-19 | — | — | US | disclosed |
| EP-3524277-A1 | PSMA-TARGETING COMPOUND AND USES THEREOF | The Johns Hopkins University (US) | 2019-08-14 | — | — | EP | disclosed |
| US-9884132-B2 | Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |
| US-20170049912-A1 | HOMOMULTIVALENT AND HETEROMULTIVALENT INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-23 | — | — | US | disclosed |
| US-20170049912-A1 | HOMOMULTIVALENT AND HETEROMULTIVALENT INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-23 | — | — | US | disclosed |
| US-9371360-B2 | Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140341804-A1 | HOMOMULTIVALENT AND HETEROMULTIVALENT INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PMSA) AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-11-20 | — | — | US | disclosed |
| WO-2013082338-A1 | HOMOMULTIVALENT AND HETEROMULTIVALENT INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PMSA) AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049912-A1 | HOMOMULTIVALENT AND HETEROMULTIVALENT INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND USES THEREOF | KLK3, UTS2R, UROD | FOLH1 4/4885GLP1R 680/4885RIMKLA 728/4885 |
| US-10653806-B2 | Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof | KLK3, UTS2R, PSMA1 | FOLH1 5/4885GLP1R 722/4885RIMKLA 775/4885 |
| US-20140341804-A1 | HOMOMULTIVALENT AND HETEROMULTIVALENT INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PMSA) AND USES THEREOF | PSMA1, KLK3, PSMA2 | FOLH1 6/4885GLP1R 699/4885RIMKLA 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.